Zieve's syndrome

Clinically encountered acute metabolic condition in alcoholic fatty liver and cirrhosis 

Clinical triad 

• Jaundice 
• Hyperlipidemia 
• Haemolytic anaemia

Zollinger-Ellison syndrome (ZES)

Inheritance : Sporadic or Autosomal dominant associated with multiple endocrine neoplasia type 1 (MEN 1)

• Multiple atypical often recurrent peptic ulcer 
• Non–beta islet cell, gastrin-secreting tumor of the pancreas : Hypergastrinemia 
• Increased gastric levels, positive secretin stimulation and calcium infusion test, abdominal CT can detect this syndrome 

Treatment 

• Proton pump inhibitors : mainstay 
• Surgery : severe cases